Publications by authors named "L Guimaraes"
Introduction: The COVID-19 pandemic changed the daily lives of university students and affected their mental health. The aim of this study was to assess the feelings and perceptions regarding the pandemic and teaching, and to identify the mental health symptoms perceived by pharmaceutical sciences students at a Brazilian public university.
Methods: This is a cross-sectional study with data triangulation (mixed-methods approach), conducted online with semiannual data collection from May 2020 to May 2021.
Seasonal monitoring, ecological risk assessment, and prioritization of pharmaceuticals in a tropical semi-enclosed bay (Santos, São Paulo coast, Brazil).
Mar Environ Res
December 2024
Research on the occurrence and seasonal monitoring of pharmaceutically active compounds (PhACs) in estuarine and coastal waters has intensified recently. However, few studies have been conducted with PhACs flowing into the marine waters of South America (such as Brazil). Against this backdrop, the aims of this study were: (i) evaluate, for the first time, the seasonal occurrence throughout a year and the potential ecological risks of ten selected PhACs in marine bathing waters from Santos Bay, São Paulo, Brazil (a tropical low-wave energy semi-closed bay); and (ii) develop a list of high-priority PhACs for the monitoring based on "occurrence, persistence, bioaccumulation, and toxicity" criteria (OPBT).
View Article and Find Full Text PDFThe effects of a single feeding cycle followed by a continuous aeration phase (AND) and a step-feeding cycle followed by intermittent aerobic/idle phases (AND) on the production and emission of nitrous oxide (NO) from aerobic granular sludge (AGS) from real domestic sewage were studied. Higher NO emissions were observed in the AND treatment, and 9.2 ± 4.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to assess how the perfusion index (PI) response to a specific stress test can indicate sympathetic-vascular reactions in patients with sepsis compared to healthy individuals and critically ill patients without sepsis.
- Three groups were analyzed: healthy patients (Group A), critically ill patients without sepsis (Group B), and septic patients (Group C), focusing on their hemodynamic responses and changes in the perfusion index during a semiorthostatic stress test.
- Findings showed that healthy individuals exhibited expected changes in cardiac function, while septic patients displayed variable responses; notably, those with a decreased perfusion index after the test had better outcomes (lower SOFA scores) after 72 hours, suggesting that monitoring the PI may
Article Synopsis
- Cutaneous leishmaniasis (CL) is linked to a positive skin test (LST) that indicates the presence of immune T cells specific to disease antigens, with this study focusing on the differences between LST+ and LST- patients.
- LST- patients showed larger lesions, a longer duration of illness, more treatment failures with meglumine antimonate, and higher healing times compared to LST+ patients.
- The study suggests that LST- patients have an impaired Th1 immune response, characterized by higher parasite loads, lower granuloma frequency, increased CD8+ T cells, and excess Granzyme B production, leading to more severe disease.