Rectal dihydroartemisinin versus intravenous quinine in the treatment of severe malaria: a randomised clinical trial.

Objective: To compare the clinical efficacy and safety of rectal dihydroartemisinin (DATM--Cotecxin) and intravenous quinine in the treatment of severe malaria in children and adults.

Setting: Moi Teaching and Referral Hospital, Eldoret, Kenya between July and November 1998.

Patients: A total of sixty seven patients aged two to sixty years with severe malaria were studied.