Custom Ocular Prosthesis: A Case Report.

Ocular prostheses play a vital role in restoring the appearance and functionality of the eye for individuals who have suffered from eye loss due to trauma, surgery, tumors, or congenital eye defects. This case report presents the successful fabrication and fitting of a custom-made ocular prosthesis for a patient with an eye defect. The process involved careful examination and digital imaging for the fabrication of prostheses.

Marginal Adaptation of Veneers: A Systematic Review.

This study aimed to systematically review the literature to evaluate the marginal adaptation of veneers using different fabrication methods, namely, conventional feldspathic porcelain laminate veneers (PLVs), computer-aided design-computer-aided machining (CAD-CAM) veneers, and pressed veneers. A comprehensive literature search was performed using electronic databases (PubMed and Google Scholar) as well as hand searches to identify all relevant studies related to veneers and marginal adaptation. The identified studies were screened for assessing the inclusion and exclusion criteria.

Customized toothbrush handle for patients with limited manual dexterity.

Elderly people may have difficulty in grasping and holding tooth brush due to limited hand and finger movement. This article describes a technique of increasing the volume of toothbrush handle with acrylic device that is custom molded to the patient's unique hand. The customized handle will make holding the brush easier and more comfortable thereby contributing to the maintenance of oral hygiene.

Concise Synthesis of 1,1-Diarylvinyl Sulfones and Investigations on their Antiproliferative Activity Tubulin Inhibition.

Background: Discovery of small molecules that inhibit tubulin polymerization is an attractive strategy for the development of new and improved anti-proliferative agents.

Objective: A series of novel 2-sulfonyl-1,1-diarylethenes were designed towards this end keeping in view the favorable chemical and pharmacological virtues of unsaturated sulfones.

Methods: Rapid, convenient and efficient two-step assembly of the designed molecules was achieved by the vicinal iodo-sulfonylation-Suzuki coupling sequence.