Publications by authors named "L Grecu"

Article Synopsis
  • The hepatitis D virus (HDV) causes severe liver damage, particularly in individuals already infected with chronic hepatitis B virus (HBV), making it a significant health concern.
  • A study in Romania clinically characterized 82 patients with HDV and identified that all belonged to the HDV-1 genotype, revealing connections to groups in Italy, France, Spain, and parts of the Middle East.
  • The findings emphasize the importance of understanding HDV epidemiology in Romania and suggest that migration patterns impact the distribution of the virus without affecting clinical outcomes among different patient clusters.
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Cervical cancer (CC) is the fourth most common cause of cancer-related deaths amongst women worldwide. CC represents a major global healthcare issue, and Romania ranks the worst in mortality rates amongst EU countries. However, the early detection of CC can be lifesaving.

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Approximately 62-72 million people are infected worldwide with HDV. Patients with chronic hepatitis D (CHD) have a higher risk of developing cirrhosis or hepatocellular carcinoma (HCC) and an increased mortality rate compared to those with chronic hepatitis B (CHB). The stage of liver fibrosis or the risk of developing HCC can also be estimated by non-invasive scores, which are cost effective, easier to apply, and reproducible.

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Objective: To evaluate the effects of droxidopa or atomoxetine on intravenous (IV) vasoactive agent discontinuation in cardiothoracic intensive care unit (ICU) patients with hypotension refractory to midodrine.

Design: Single-center, retrospective cohort study.

Setting: Tertiary- and quaternary-care university teaching hospital.

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