Publications by authors named "L Gonzalez-Baranda"
Article Synopsis
- - The study investigates how the innate immune system, specifically NK and NKT cells, responds in individuals infected with SARS-CoV-2, noting variations between severe and mild cases of COVID-19.
- - Results showed that severe COVID-19 patients had lower frequencies of NK cells and abnormal expressions of important receptors compared to those with milder illness and healthy controls.
- - The findings imply that the dysfunctional behavior of NK and NKT cells in severe cases may influence disease severity and outcomes across different populations.
A detailed quantitative analysis of circulating T peripheral and follicular helper lymphocytes in patients with rheumatoid arthritis and systemic lupus erythematosus.
Reumatol Clin (Engl Ed)
November 2024
Introduction And Objective: Peripheral and follicular helper T lymphocytes (Tph and Tfh, respectively) have an important role in B cell immune responses and the pathogenesis of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Although several studies on the number of Tph and Tfh cells in these conditions have been published, different phenotypes have been employed for their analysis. In this study, we assessed the levels and function of Tph and Tfh cells in blood samples from patients with RA and SLE by using an extended immunophenotype.
View Article and Find Full Text PDFBackground: Type 2 diabetes mellitus (T2DM) is usually accompanied by a low-grade inflammatory phenomenon, which participates in the pathogenesis of different complications of this condition. The inflammatory response is under the regulation of different mechanisms, including T regulatory (Treg) lymphocytes. However, the possible role of type 1 T regulatory (Tr1) cells in T2DM has not been explored so far.
View Article and Find Full Text PDFObjective: To analyze the possible in vitro effect of the cytokine RANKL and bacteria involved in apical periodontitis on the differentiation of macrophages into osteoclasts.
Material And Methods: Bacteria were isolated (mainly E. faecium and E.
A low-grade inflammatory phenomenon is a feature of overweight and metabolic syndrome. The involvement of a pro-inflammatory Th17 lymphocyte subset and the CD69+ T regulatory (Treg) cell subtype in patients with metabolic dysfunction associated with or without overweight has not been fully elucidated. The aim of this study was to perform a quantitative and functional analysis of pathogenic Th17 lymphocytes and CD69+ Treg cells in patients with metabolic dysfunction (insulin resistance and dyslipidemia).
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