Screening for colon cancer: A test for occult blood.

Background: The relevance of the problem of colorectal cancer (CRC) is evident because of extremely high morbidity and mortality rates, associated with this disease. CRC is mostly diagnosed only at very advanced stages. The reduction of mortality can be achieved by the popularization of screening-methods for early identification of CRC and adenomatous polyps of the colon, which are proved to be precancerous condition.

[Efficacy of intravenous iloprost (Ilomedin®) in salvage of the only extremity in a patient with thrombangiitis obliterans].

Buerger s disease, or thromboangiitis obliterans, is a severe invalidating systemic vascular disease. The present article deals with a clinical case report concerning treatment of a patient suffering from thromboangiitis obliterans with three limbs amputated (on the background of therapy with alprostadil, Karavanov s mixture, rheopolyglukin, pentoxyphyllin). The course intravenous administration of the stable analogue of prostacyclin - iloprost (IlomedinR) made it possible to save the only extremity.

[Optimal diagnostic criteria of ENT manifestations of GERD].

Background: GERD has a number of extraesophageal manifestations (EEM) such as ENT, pulmonary etc. 24-hours pH monitoring in distal esophagus is widely used to confirm the diagnosis but its cut-off values for the diagnosing of extraesophageal manifestations of GERD (for example ENT) are unknown.

Aim: To evaluate the optimal cut-off values for mean pH, time pH < 4 a day in the proximal esophagus and number of high gastroesophageal refluxes (HGR) in regard to presence of extraesophageal manifestations of GERD.

[Value of the high gastroesophageal reflux registration in the diagnosis of extraesophageal manifestations of GERD].

Introduction: The 24-hours pH-monitoring is the "gold standard" to verify the presence of pathologic reflux and confirmation of GERD. But there is lack of data whether it is helpful to verify the link between extraesophageal manifestations with GERD.

Aim: To evaluate the utility of proximal 24-hours pH monitoring for diagnosing ENR manifestations of GERD.