Publications by authors named "L Garzarella"
Aim: To determine the relative frequency of type 2 diabetes mellitus (DM) in the US, and to assess diabetes practice patterns in the US.
Method: A questionnaire regarding pediatric diabetes practice patterns was distributed to the members of the Lawson Wilkins Pediatric Endocrine Society in 1999. Only one member of each practice group was requested to respond.
Context: Although cancers occur with increased frequency in children with human immunodeficiency virus (HIV) infection, the specific clinical, immunological, and viral risk factors for malignancy have not been identified.
Objective: To identify risk factors for malignancy among HIV-infected children.
Design, Setting, And Patients: A multicenter case-control study of children with HIV at 26 institutions participating in the Pediatric Oncology Group.
An optimal platelet-count threshold for prophylactic platelet transfusion in hematopoietic stem cell transplant (HSCT) recipients has yet to be determined. Between July 1997 and December 1999, we performed the first prospective randomized clinical trial addressing this issue in 159 HSCT recipients who received a prophylactic platelet transfusion when the morning platelet count fell below a 10,000/microL (10K) or 20,000/microL (20K) threshold. Subsequent prophylactic transfusions were administered according to a predetermined algorithm.
View Article and Find Full Text PDFPurpose: To investigate the prognostic significance of surveillance neuroimaging for detection of relapse among children with malignant brain tumors.
Patients And Methods: A historical cohort study examined all children who experienced relapse from 1985 to 1999 on one of 10 Pediatric Oncology Group trials for malignant glioma, medulloblastoma, or ependymoma.
Results: For all 291 patients (median age at diagnosis, 8.