Publications by authors named "L Garcia-Otero"
Article Synopsis
- Perinatal mortality is notably high in low- and middle-income countries, with accurate fetal gestational age assessment essential for differentiating between prematurity and intrauterine growth restriction for better management strategies.
- The study conducted in Barcelona sought to validate post-mortem ultrasound measurements of the cerebellum as a method for estimating gestational age in cases of fetal and perinatal deaths.
- Findings demonstrated a strong correlation between various cerebellar measurements and gestational age, with the extrauterine transcerebellar diameter emerging as the most reliable predictor, regardless of the trimester in which the measurement was taken.
Introduction: Pregnant women have an increased risk of severe COVID-19. Evaluation of drugs with a safety reproductive toxicity profile is a priority. At the beginning of the pandemic, hydroxychloroquine (HCQ) was recommended for COVID-19 treatment.
View Article and Find Full Text PDFStudy Question: Do spontaneously conceived (SC) fetuses from subfertile couples show the same signs of cardiac remodeling as those observed after IVF treatments?
Summary Answer: As opposed to fetuses from IVF, SC fetuses from subfertile couples do not show cardiac remodeling and present a similar cardiac structure and function to those of SC fetuses from fertile couples.
What Is Known Already: Subjects conceived by IVF present signs of cardiac remodeling and suboptimal function in utero and during childhood, including larger atria, more globular and thicker ventricles, reduced longitudinal motion, and impaired relaxation as compared to SC individuals from fertile couples. There are no previous publications investigating the independent cardiac programming effects of infertility in SC fetuses from subfertile couples (with time-to-pregnancy (TTP) over 12 months).
SARS-CoV-2 Seropositivity and HIV Viral Load Among Mozambican Pregnant Women.
J Acquir Immune Defic Syndr
February 2023
Introduction: Prevalence estimates of SARS-CoV-2 infection in Africa are limited, particularly among pregnant women and in those living with HIV. This study assessed the seroprevalence of SARS-CoV-2 antibodies among Mozambican HIV-infected pregnant women during the first year of the pandemic, before COVID-19 vaccines were deployed in the country.
Setting: The study was conducted in Manhiça district, a semirural area in southern Mozambique.
Background: Information on the frequency and clinical features of advanced HIV disease (AHD) in pregnancy and its effects on maternal and perinatal outcomes is limited. The objective of this study was to describe the prevalence and clinical presentation of AHD in pregnancy, and to assess the impact of AHD in maternal and perinatal outcomes in Mozambican pregnant women.
Methods: This is a prospective and retrospective cohort study including HIV-infected pregnant women who attended the antenatal care (ANC) clinic at the Manhiça District Hospital between 2015 and 2020.