The role of urinary potassium in the pathogenesis and diagnosis of interstitial cystitis.

Purpose: We determined whether intravesical potassium absorption in normal bladders correlates with increased sensory urgency, and corroborated the hypothesis that mucus is important in the regulation of epithelial permeability. We compared sensory nerve provocative ability of sodium versus potassium, and determined whether intravesical potassium sensitivity discriminates patients with interstitial cystitis from normal subjects and those with other sensory disorders of the bladder.

Materials And Methods: A total of 231 patients with interstitial cystitis and 41 normal subjects underwent intravesical challenge with 40 ml.

The effect of postmenopausal estrogen therapy on the risk of non-insulin-dependent diabetes mellitus.

Objectives: This study examined the effect of postmenopausal estrogen replacement therapy on the incidence of non-insulin-dependent diabetes in women.

Methods: Postmenopausal women aged 50 through 70 years (n=848) without diagnosed diabetes at baseline were followed for 10 to 15 years for incident diabestes.

Results: Over the average 11.