[Tissue reactions in children treated with hemodynamic dextran and detoxication polyvinylpyrrolidone plasma substitutes].

By means of light and electron microscopy tissue reactions produced by repeated use of polyvinylpyrrolidone (PVP) and dextran plasma substitutes are studied on the material of 20 autopsies and 4 biopsies as well as in 65 experimental cases. Delayed type of PVP accumulation in tissues after the hemodes administration is determined as well as its dependence on the dose, time, kidney function and the presence of inflammatory foci. The differences in tissue reactions after administration of dextran and PVP substitutes are established.

[Sorption unit for regeneration of dialysis solution in artificial kidney].

The authors present the results of the tests of an adsorption unit model for a renal dialyzer comprising ligand-metabolic material. The solution is effectively purified of urine, ammonium, creatinine, uric acid, sulphates and phosphates. Hydrodynamic properties of the unit were investigated.

[Correction of disorders of systemic hemodynamics and rheologic indices of the blood in patients with chronic kidney failure during hemodialysis].

During hemodialysis, 44 patients with terminal chronic renal failure were examined for the systemic hemodynamics and blood rheological properties as well as for the possibility of their correction by infusion of the plasma substitutes: polyglucine, rondex or 10% albumin at a volume of 400 ml per administration. It was established that patients on hemodialysis manifested pronounced hemodynamic and rheological disorders. During hemodialysis, the hemodynamic disorders correlated with the changes in the rheological properties of the blood (r = 0.

[Preparation of lysozyme immobilized on textile carriers and its use in treating suppurative wounds].

Immobilized forms of lysozyme were prepared by its covalent binding on dialdehyde cellulose and polycaproamide fibres as woven and knitted fabrics respectively. The preparations were estimated by the content of protein and bacteriolytic activity. The lysozyme activity per 1 g of the carrier and the protein content on dialdehyde cellulose were several times higher than those on polycaproamide while the specific activity of lysozyme on the polycaproamide carrier was somewhat higher than that on dialdehyde cellulose.

[Comparative evaluation of the effectiveness of biologically active and regular drainage in the prevention of disorders of wound healing].

An analysis of clinical material on 35 patients with pyo-inflammatory processes in soft tissues is presented which were treated using biologically active drains. The cytological and cytochemical investigations have shown that draining properties of the biologically active drains are much better than those of the chlorvinyl and silicon drains.