[The hemodynamic, humoral and cellular effects of plasmapheresis in a refractory form of hypertension].

Plasmapheresis effects on hemodynamics, neurohumoral, immunological and cell parameters were examined in 48 patients with refractory hypertension. Hypotensive effect of plasmapheresis was found to combine with positive hemodynamics and microcirculatory shifts, pressor factor activity inhibition, slowing of immunocomplex condition progress, reduced red cell deformability in refractory hypertension.

[The clinico-rheoencephalographic characteristics of a hyperemia syndrome].

The author present comparative analysis of rheoencephalographic (REG) data obtained from 500 differently aged Kiev residents with atherosclerotic dyscirculatory encephalopathy after Chernobyl accident. Changes of principal REG parameters are determined as the plethoric syndrome (PS). Main variants of nerves characterizing PS are divided into three types.

[Humoral immunity in young hypertension patients].

The state of humoral immunity was investigated in 72 young-age patients suffering of hypertensive disease. It was established that there occurred an increase of the level of immunoglobins, circulating immune complexes and antibodies to lipoproteids of low density in hypertensive disease. This indicates the importance of immunological changes in the pathogenesis of hypertensive disease.

[The effect of propranolol on the apoprotein spectrum of the blood plasma in patients with ischemic heart disease].

The authors studied the effect of anaprilin monotherapy (dose: 160-200 mg/daily for 10 months) on the level of atherogenic apolipoproteins (apo A, apo B) and fractions of plasma cholesterol in 34 patients with ischemic heart disease, stable exertion angina pectoris (class 2-3). It was established that changes in the plasma lipid and apoprotein spectrum result in an increase of apo B, decrease of apo 1, increase of apo B/apo A1, decrease of high-density lipoprotein cholesterol (HDLCS) and a different dynamics of HDLCS/apo A1. The established changes in the lipid metabolism are of atherogenic character.

[The content of fibronectin, fibrinogen, its degradation products and myoglobin in patients with ischemic heart disease].

ELISA using the test systems and a complex of equipment manufactured by Flow Company was employed to study over time the content of fibronectin, fibrinogen, products of its degradation and myoglobin in 178 patients suffering from coronary heart disease (stable and progressive angina pectoris, acute myocardial infarction). The concentration of myoglobin, fibronectin, fibrinogen and products of its degradation was established to depend on the gravity of coronary heart disease and the tame elapsed since the disease onset. In patients with progressive disease, there was an increased consumption of fibronectin which may be due both to its expenditure during blood coagulation and fulfillment of angioprotective function because of exacerbation of systemic atherosclerosis.