Bronchiectasis Occurs Independently of Chronic Obstructive Pulmonary Disease in Alpha-1 Antitrypsin Deficiency.

Introduction: Bronchiectasis occurs in patients with alpha-1 antitrypsin deficiency (AATD), but it is unknown whether an association exists independently of chronic obstructive pulmonary disease (COPD). We assessed whether bronchiectasis was associated with COPD in our cohort, and whether it has clinical significance for lung function decline, exacerbation rate, or symptoms.

Study Design And Methods: PiZZ, PiSZ, and PiMZ patients from the Birmingham AATD Research Database were studied.

Trust, confidence, familiarity, and support for land-based recirculating aquaculture facilities.

Surveys in three U.S. localities (n = 523) with proposed or existing land-based aquaculture facilities probed trust's relationship with perceived net benefits and public intentions to cooperate with siting of this novel technology.

The Semantics of 'Hip Pain' and its Impact on Clinical Practice in Patient-Reported Outcome Measures (PROMs) of Disease: Results from a Clinical and Radiological Evaluation Cohort.

Introduction: The item 'hip pain' is widely used in questionnaires related to Spondyloarthritis and/or Ankylosing spondylitis (AS), either in clinics with patients being physically present or remotely, as the hip joint is known to affect AS in particular. Patients in clinics often claim to have hip pain. However, by stating "hip" they are referring to variable structures located in the hip region not necessarily related to hip joint itself.

Support for deer herd reduction on offshore Islands of Maine, U.S.A.

Over the past three decades, citizens of Maine in the northeastern United States have experienced increasing blacklegged tick (Ixodes scapularis) abundance and rising incidence of Lyme and other tick-borne diseases. White-tailed deer (Odocoileus virginianus) overabundance has been considered one cause of the high incidence of tick-borne diseases on offshore islands of New England. Most of Maine's 15 offshore, unbridged island communities have a history of concern about ticks, Lyme disease, and white-tailed deer overabundance, but have been challenged to keep deer numbers down through hunting or culls.

Pragmatic and (or) Constitutive? On the Foundations of Contemporary Risk Communication Research.

A diffuse and interdisciplinary field, risk communication research, is founded on how we understand the process and purpose of communication more generally. To that end, this article outlines two fundamental functions of risk communication: (1) a pragmatic function, in which senders direct messages at audiences (and vice versa), with various intended (and sometimes unintended) effects; and (2) a constitutive function, in which messages re(create) what we mean by "risk" in a given social context, including how we can, and/or should relate to it. Although representing distinct epistemological and theoretical social scientific traditions, these functions necessarily coexist in a broader understanding of risk communication, including its so-called "effectiveness.