Publications by authors named "L G Pavelkovskaia"

Cell suspensions of Legionella pneumophila, a virulent Philadelphia I strain, were incubated with rabbit antiserum to type-specific heat-sensitive antigen III having toxic properties with the use of the indirect immunoferritin technique. Antigen III was localized in the outer fibrillar microcapsule-like layer 12-20 mm thick. In the direct immunoperoxidase test antigen III had globular localization on the cell wall surface.

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Radioimmunological method with the aid of standard sets was applied to determination of the content of chorionic gonadotropin, placental lactorgen, prolactin, folliculo-stimulating and luteinizing hormones in the immunoglobulin preparations made of abortion and placental blood serum. Serum fractionation by Cohn's method (technological variant B) led to reduction in the immunoglobulin preparations of polypeptide hormones (placental lactogen and prolactin) content, but it was not sufficiently effective in respect to glucoprotein hormones.

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The authors carried out a comparative quantitative and biological determination of gonadotropins in 32 batches of immunoglobulin preparations made of the abortive, placental, and donor blood sera. The maximal amounts of gonadotropins were contained in preparations obtained from the abortive blood serum. It was shown that purification by Kohn's method (variant B) led only to the partial purification of immunoglobulins from the gonadotropin admixtures.

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