Publications by authors named "L G M van der Geest"
Article Synopsis
- - The study examined survival scenarios for pancreatic adenocarcinoma (PAC) patients over 16 years, highlighting best-case, typical, and worst-case survival estimates based on data from the Netherlands Cancer Registry.
- - Patients with localized PAC showed statistically significant improvements in best-case and typical survival scenarios, with gains averaging 1.54 and 0.24 months annually, respectively, while those with metastatic PAC experienced smaller but significant improvements.
- - Factors like age, aggressive treatments, and fewer comorbidities were linked to better survival outcomes, suggesting that recent advancements in care may offer hopeful prospects for PAC patients, despite small absolute survival gains.
Objective: The impact of the coronavirus disease 2019 (COVID-19) on hepatocellular carcinoma (HCC) care is unclear. This study reports on HCC patterns during the COVID-19 pandemic in the Netherlands.
Methods: Patients diagnosed with HCC between 2017 and 2020 were identified from the Netherlands Cancer Registration.
Article Synopsis
- The study aimed to assess treatment outcomes, overall survival (OS), and factors influencing OS in patients with T1 ampullary cancer, a rare type of gastrointestinal cancer.
- Out of 244 patients with clinical T1 ampullary cancer, 75% underwent surgery, but a significant number were found to have more advanced disease upon further examination.
- The results indicated a stark difference in survival based on disease classification, with poor prognostic factors including higher pathological N classification and poorly differentiated tumors, emphasizing the need for aggressive treatment like pancreatoduodenectomy for T1 cases.
Introduction: Sex and gender are modulators of health and disease and may have impact on treatment allocation and survival in patients with cancer. In this study, we analyzed the impact of sex and gender on treatment allocation and overall survival in patients with stage I-III pancreatic cancer.
Methods: Patients with stage I-III pancreatic cancer diagnosed between 2015 and 2020 were selected from the nationwide Netherlands Cancer Registry.
Importance: Implementation of new cancer treatment strategies as recommended by evidence-based guidelines is often slow and suboptimal.
Objective: To improve the implementation of guideline-based best practices in the Netherlands in pancreatic cancer care and assess the impact on survival.
Design, Setting, And Participants: This multicenter, stepped-wedge cluster randomized trial compared enhanced implementation of best practices with usual care in consecutive patients with all stages of pancreatic cancer.