[Hyperprolactinemia associated with neuroleptic treatment: clinical characteristics and an impact on sexual function].

Aim: To study clinical characteristics of antipsychotic-induced hyperprolactinemia (AIH) and an impact of AIH on sexual function in patients with mental disorders treated with neuroleptics for a long time.

Material And Methods: A cross-sectional study of 244 consecutive psychiatric in-patients (F/M=140/104) with mental disorders currently taking antipsychotics was carried out. The patients were screened for serum prolactin, sex hormones and gonadotropin levels.

Synthesis of monodisperse, covalently cross-linked, degradable "smart" microgels using microfluidics.

The development of a robust method for the synthesis of highly monodisperse microgels cross-linked with degradable covalent bonds offers the potential for fabricating microgels with the highly controllable porosities, cell interactions, and degradation half-lives required for biomedical applications. A microfluidic chip is designed that enables the on-chip mixing and emulsification of two reactive polymer solutions (hydrazide and aldehyde-functionalized carbohydrates) to form monodisperse, hydrazone cross-linked microgels in the size range of ≈40-100 μm. The device can be run continuously for at least 30 h without a significant drift in particle size.

[Sensory-pain adaptation in clinical neurology].

The article presents quantitative (temporal) and qualitative (phenomenological) characteristics of sensory-painful adaptation in clinically healthy subjects of various age and in patients with neuroses and organic lesions of different levels and of variable genesis. It has been ascertained that investigation of sensory-painful adaptation may be of a certain diagnostic significance.