[Effect of disruption of the entopeduncular nucleus on rat behavior in simultaneous discrimination and open field tests]].

The influence of unilateral destruction of n. entopeduncularis on learning and retention of simultaneous discrimination in a T-maze and adaptation in the open filed was studied in 29 adult rats. Destruction of n.

[Extinction of the defensive conditioned reflex in cats after lesioning the endopeduncularis nucleus].

Influence of bilateral destruction of nucleus entopeduncularis on the extinction of conditioned avoidance was studied in 10 adult cats. It was shown that bilateral destruction of the nucleus entopeduncularis led to a disturbance of storage of the previous conditioning and facilitated repeated extinction.

[Comparative study of three antineoplastic alkylating agents on DNA].

The influence of three alkylating anticancer preparations phosphamide, sarcolysine, cyclophosphane on content of the 5-methylcytosine and parameters of the melting DNA of the liver healthy animals and tumor sarcoma 45 was investigated. It was shown, that among the investigated preparations cyclophosphane has stronger anticancer influence and comparatively weaker side effect on DNA liver. We came to the conclusion that it is preferable to use this preparation.

[Features of melting of DNA complexes with mitoxantrone at low concentrations].

The melting of DNA complexes with the anticancer mitoxantrone preparation at the mu = 0.11 and mu = 0.011 NaCl ionic strengths was investigated by the methods of microcalorimetry and spectrophotometry.