Publications by authors named "L G Hvid"

Unlabelled: This review investigated the psychometric properties of the most commonly used short-, long-, complex- and patient-reported walking outcome measures in multiple sclerosis(MS): the timed-25-foot walk test (T25FW), the six-minute walk test (6MWT), the six-spot step-test (SSST), and the 12-item MS walking scale (MSWS-12), along with reported reference data of these tests.

Methods: Based on PubMed and Embase searches, psychometric as well as descriptive data of T25FW, 6MWT, SSST, and MSWS-12 were extracted from studies evaluating persons with MS (pwMS). Descriptive data was also extracted from healthy controls (HC), if reported.

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Introduction: Multiple sclerosis has a substantial negative impact on physical activity (PA). However, limited knowledge exists on objectively measured PA levels and types across disability status along with its influence on walking capacity.

Objectives: To (1) determine PA levels/types in persons with MS (pwMS) (overall and across disability status) and in healthy controls (HC), and (2) investigate the association between PA levels/types and walking capacity.

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Unlabelled: This study examines how power training affects estimated bone strength, revealing that females benefit more than males, especially in the upper limbs (radius). These findings highlight the importance of designing sex-specific exercise programs to enhance bone health. Further research is needed to optimize training duration and address site-specific differences.

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Article Synopsis
  • Older people with multiple sclerosis (pwMS) are at a higher risk for sarcopenia, which means they may experience decreased muscle mass, strength, and function, and this issue is not well-studied in this population.
  • This study analyzed 41 older pwMS and 27 healthy controls using the EWGSOP2 diagnostic tool and focused on their muscle strength in both upper and lower extremities.
  • Results revealed that older pwMS had significantly lower muscle strength, especially in their lower extremities, and concluded that lower extremity tests are more effective for diagnosing sarcopenia in this group.
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  • Chronic inflammatory diseases (CIDs) are increasingly challenging for healthcare, with many patients responding poorly to biological treatments, leading to interest in dietary changes, particularly gluten-free diets.
  • This study explored the effect of gluten intake on the clinical response to biological treatment over 14-16 weeks in 193 CID patients, comparing those with high gluten intake to those with low-to-medium intake.
  • Results showed no significant differences in treatment response or secondary outcomes, indicating that gluten intake does not influence the effectiveness of biological therapy in patients with CIDs.
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