Publications by authors named "L G Frenken"
The role of urine sodium in acutely decompensated heart failure.
Int J Cardiol Heart Vasc
December 2024
Article Synopsis
- Diuretic resistance is when medications that help remove extra fluid from the body don’t work well, which can lead to worse health outcomes for patients with heart problems. Researchers looked at how urine sodium levels (how much sodium is in urine) can help adjust these medications to make them more effective.
- The study included 143 patients with heart failure, and they found that those with low urine sodium levels also had other health issues. They measured urine sodium two hours after giving medicine to patients and looked at how this affected hospital visits and overall survival after 90 days.
- The results showed that low urine sodium was common and often found in patients with serious heart and kidney problems,
Background: Recent studies showed a high prevalence of monoclonal gammopathy (MG) in patients with thrombotic microangiopathy (TMA) aged over 50 years and suggested that complement dysregulation is pivotal for the disease to develop. Here, we studied this premise in seven patients with TMA and coexisting MG.
Methods: Patients with TMA on kidney biopsy and/or peripheral blood were recruited from the prospective COMPETE cohort (NCT04745195) and Limburg Renal Registry.
The wild carrot () is famous for its dark flowers in the umbel centre. Several studies have been conducted to figure out their functional significance, but the evolution of the dark centre remains an enigma. In the present paper, we consider all known apioid species with dark-centred umbels to get a deeper understanding of their biology and evolution.
View Article and Find Full Text PDFEffect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial.
Am J Clin Nutr
January 2019
Background: Evidence on the effect of small-quantity lipid-based nutrient supplements (SQ-LNSs) on early child growth and development is mixed.
Objective: This study assessed the effect of daily consumption of 2 different SQ-LNS formulations on linear growth (primary outcome), psychomotor development, iron status (secondary outcomes), and morbidity in infants from age 6 to 12 mo within the context of a maize-based complementary diet.
Methods: Infants (n = 750) were randomly assigned to receive SQ-LNS, SQ-LNS-plus, or no supplement.