Publications by authors named "L G Danielsson"
Malaria caused by Plasmodium falciparum leads to the destruction of red blood cells (RBCs). A better understanding of how naturally immune individuals control infections should be valuable for future vaccine studies. Antibodies against RBCs and RBC surface antigens were measured together with different inflammatory markers in healthy adults living in a malaria endemic area of Uganda and compared to Swedish healthy adults.
View Article and Find Full Text PDFArticle Synopsis
- Malaria, particularly caused by the Plasmodium falciparum parasite, poses a major public health issue, and osteopontin (OPN) plays a role in regulating the immune response during acute malaria, though its exact effects in humans are not fully understood.
- Blood samples from various groups, including Swedish adults and Ugandan patients, indicated that OPN levels were significantly higher during acute malaria infection, especially in children, with correlations found between OPN, interferon-γ, and parasite levels.
- The study concludes that elevated OPN levels in acute malaria relate more closely to a lack of immunity rather than age, highlighting OPN's potential significance in understanding malaria, especially in individuals who are not immune.
Background: Production of anti-phosphatidylserine (anti-PS) antibodies has been associated with malaria and can aggravate pathology. How these autoantibodies develop during early childhood in a malaria context is not known. We examined levels of anti-PS IgG and IgM antibodies in a longitudinal cohort of mother-baby pairs during birth, in the infants at 2.
View Article and Find Full Text PDFExperiences of rehabilitation coordination among people on sick leave with mental health problems.
Scand J Prim Health Care
December 2024
Purpose: Return to work often requires collaboration between different stakeholders. Rehabilitation coordination is a resource in coordinating efforts during sick leave to facilitate return to work. The purpose of the present study was to describe how people at risk for sick leave or on sick leave with mental health problems experienced rehabilitation coordination.
View Article and Find Full Text PDFArticle Synopsis
- The study explored the effects of 12-week exercise interventions on health-related quality of life (HR-QoL), work ability, and sick leave among anxiety disorder patients, with follow-up assessments after one year.
- Among 222 participants, those in the moderate/high-intensity exercise group showed significant improvements in HR-QoL and work ability compared to the control group after 12 weeks and at one year, particularly for those also taking antidepressants.
- Limitations included a high dropout rate, mostly early on, which is common in anxiety treatment studies; however, the findings suggest that higher intensity exercise can benefit anxiety patients' overall quality of life.