The effects of sensitization protocols on arthritic responses in antigen-induced arthritis.

Three different immunization protocols were studied for their effect on methylated bovine serum albumin (mBSA)-induced arthritis. Mice were immunized with mBSA in Freund's incomplete adjuvant containing dextran and challenged 3 weeks later with antigen in one knee. After 7-14 days a strong inflammatory reaction developed without significant erosions of articular cartilage or bone.

Evaluation of angiogenesis in chronic inflammation by laser-Doppler flowmetry.

1. A non-invasive method is described for the assessment of angiogenesis in chronic inflammation using laser-Doppler flowmetry. 2.