Publications by authors named "L G Cruz-Gomez"
Article Synopsis
- Mycetoma is a chronic infection affecting subcutaneous tissue, often linked to environmental factors like rainfall and temperature, with gaps in knowledge concerning its geographic distribution and ecological niches.
- A study of 31 actinomycetoma patients in Northeast Mexico identified two main clusters based on soil type, temperature, and precipitation, revealing specific bacterial agents responsible for infections in each region.
- The project highlights the connection between past injuries from thorny plants and the occurrence of mycetoma, emphasizing the need for targeted disease management strategies in endemic areas.
Background: Mycetoma is a neglected tropical disease characterized by nodules, scars, abscesses, and fistulae that drain serous or purulent material containing the etiological agent. Mycetoma may be caused by true fungi (eumycetoma) or filamentous aerobic bacteria (actinomycetoma). Mycetoma is more frequent in the so-called mycetoma belt (latitude 15° south and 30° north around the Tropic of Cancer), especially in Sudan, Nigeria, Somalia, India, Mexico, and Venezuela.
View Article and Find Full Text PDFAlopecia areata (AA) is an autoimmune disease of the hair follicle. Keratinocytes of the hair follicle generate an immunosuppressive environment by the local secretion of hormones of the hypothalamic-pituitary-adrenal axis of the skin (skin HPA analog). Our objective was to measure the local production of corticotropin-releasing hormone (CRH), adrenocorticotropic hormone (ACTH), and α-melanocyte-stimulating hormone (α-MSH) in the scalp tissue of patients with AA before and after ultraviolet A1 (UVA-1) phototherapy to determine their role in the pathogenesis of AA and the effect of UVA-1 on the AA hormonal environment.
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