[The functional characteristics of the chromosomal nucleolus organizer regions of patients with endometrial cancer].

The nucleolus organizer region activity and the level of acrocentric chromosome association in cultured peripheral blood lymphocytes was studied in patients with endometrial glandular hyperplasia and endometrial cancer. The number of active nucleolus organizer regions and the frequency of 13 and 21 acrocentric chromosome associations was higher in patients with endometrial cancer.

[A cytogenetic examination of persons subjected to radiation exposure in certain regions of Ukraine].

We have summarized the results of cytogenetic studies of peripheral blood lymphocytes conducted in the institutions of Kiev and Kharkov in persons irradiated after the accident of the Chernobyl NPP. The average level of chromosomal aberrations and the appearance of cytogenetic markers characteristic of their irradiation effect was higher in the examinees in comparison with the control. The increase in the number of aberrations in certain Kiev residents as well as the development of lymphogranulomatosis in some liquidators of the accident were detected.

[Morphofunctional features of the nucleoli in glandular hyperplasia and endometrial cancer].

The morphofunctional peculiarities of epithelial cells nucleoli in patients with glandular hyperplasia and endometrial cancer has been studied on the cytological smears from endometrium stained with silver nitrate were investigated. The patterns of nucleolonemic nucleoli content and high activity of nucleolar organizers in cancer of corpus uteri are revealed.

[Electron microscopic and electron radioautographic study of cells in glandular hyperplasia and cancer of the endometrium].

Peculiarities of the ultrastructure and RNA synthesis in the epithelial endometrial cells of nine patients with hyperplasia and the uterine cavity cancer have been studied by the electron-radioautographic method. Quantitative differences are revealed in the ultrastructures of the cells. Amplification of the nucleoli labelling and asynchronism of the RNA synthesis in the nucleoli with glandular hyperplasia and endometrial cancer are observed.