The emergence and spread of drug-resistant pathogens, resulting in antimicrobial resistance, continue to compromise our capability to handle commonly occurring infectious diseases. The rapid global spread of multi-drug-resistant pathogens, particularly systemic fungal infections, presents a significant concern, as existing antimicrobial drugs are becoming ineffective against them. In recent decades, there has been a notable increase in systemic fungal infections, primarily caused by species, which are progressively developing resistance to azoles.
View Article and Find Full Text PDFSporotrichosis is a fungal infection occurring worldwide, especially in tropical and sub-tropical areas. We present a brief review of clinical and epidemiological aspects of sporotrichosis, as well as its treatment. Sporotrichosis is rarely reported in Europe and the European Centre of Disease Control does not track its infection rate.
View Article and Find Full Text PDFEur J Clin Microbiol Infect Dis
December 2020
An autochthonous case of lymphocutaneous sporotrichosis caused by Sporothrix schenckii is reported. The patient developed skin lesions localized along the lymphatics that appeared after he suffered an injury while collecting wicker canes in marshy water. The fungus was identified as Sporothrix schenckii by MALDI-TOF and sequencing.
View Article and Find Full Text PDFantibiotic resistance is a constantly evolving process and local surveillance is warranted to guide clinicians in the choice of therapy. Antibiotic susceptibility testing was performed by E-test on 92 strains, and resistance to clarithromycin and levofloxacin was also evaluated using a commercially available genotyping method. In naïve patients the resistance to clarithromycin, levofloxacin, and metronidazole was 37.
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