Cognitive effects of modafinil in patients with multiple sclerosis: A clinical trial.

Purpose/objective: To assess the efficacy of modafinil for the treatment of new learning and memory deficits and fatigue in multiple sclerosis. Only 1 previous study in the literature, to our knowledge, examined the effect of modafinil on cognition specifically in persons with multiple sclerosis.

Research Method/design: Sixteen patients with a diagnosis of multiple sclerosis (MS) and documented new learning impairment completed the study.