Publications by authors named "L Floyd"
Article Synopsis
- Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is a serious chronic condition that greatly affects patients' quality of life, causing high levels of fatigue, pain, depression, and anxiety.
- Although advances in treatment have improved outcomes, there’s limited understanding of the patient experience and a lack of specific tools to measure patient-reported outcomes (PROs).
- This study aims to develop a disease-specific patient-reported outcome measure (PROM) through qualitative research methods like focus groups and interviews, helping to assess key patient experiences and improve individualized care in clinical practice.
Objectives: ANCA-associated vasculitis (AAV) is associated with significant morbidity, fatigue, pain and poor health-related quality of life (HRQoL). This review aims to assess the comprehensiveness of existing patient reported outcome measures (PROMs) used in AAV and identify associations with poorer HRQoL outcomes.
Methods: A literature review of studies using PROMs, including those labelled HRQoL in people with AAV as a primary or secondary study outcome were screened and reviewed up to July 2023.
Significance Statement: Reliable prediction tools are needed to personalize treatment in ANCA-associated GN. More than 1500 patients were collated in an international longitudinal study to revise the ANCA kidney risk score. The score showed satisfactory performance, mimicking the original study (Harrell's C=0.
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