Publications by authors named "L Fleischhans"

This work investigates the detection of defunct or absent diesel particle filters by drive-through remote sensing measurement at the Czech University of Life Sciences main vehicular entrance gate. An exhaust sample was collected by a line attached to the road surface in the center of the travel lane. A non-volatile particle number (nvPN) counter and electric mobility particle size classifier were used to measure particle number concentrations, and an FTIR analyzer was used to measure CO, CO, and NO concentrations.

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Article Synopsis
  • The study examined socio-demographic characteristics, clinical presentations, and outcomes of mpox patients across 14 Central and Eastern European countries.
  • Nearly all of the 154 diagnosed patients were males, primarily men who have sex with men (MSM), with a significant proportion also living with HIV, who engaged in high-risk sexual behaviors.
  • The findings suggest a need for effective contact tracing and vaccination strategies to manage mpox outbreaks, as the majority of cases presented favorable outcomes despite some complications.
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Article Synopsis
  • There is ongoing uncertainty about the relationship between SARS-CoV-2 and HIV, specifically regarding the risks for individuals infected with both viruses.
  • A study involving 536 HIV-positive patients in central and eastern Europe revealed that low CD4 cell counts and detectable HIV viral loads are linked to increased severity of COVID-19 symptoms.
  • Findings suggest that a lower HIV viral load correlates with less severe COVID-19 outcomes, indicating its potential use as a prognostic tool for clinicians treating co-infected patients.
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HIV-positive patients may present lungs with multiple infections, which may hinder differential diagnoses and the choice of treatment in the course of COVID-19, especially in countries with limited access to high-standard healthcare. Here, we aim to investigate the association between radiological changes and poor COVID-19 outcomes among HIV-positive patients from Central and Eastern Europe. Between November 2020 and May 2021, the Euroguidelines in Central and Eastern Europe Network Group started collecting observational data on HIV and COVID-19 co-infections.

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Objectives: The aim of this international multicentre study was to review potential drug-drug interactions (DDIs) for real-life coadministration of combination antiretroviral therapy (cART) and coronavirus disease 2019 (COVID-19)-specific medications.

Methods: The Euroguidelines in Central and Eastern Europe Network Group initiated a retrospective, observational cohort study of HIV-positive patients diagnosed with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Data were collected through a standardized questionnaire and DDIs were identified using the University of Liverpool's interaction checker.

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