Resistance of Rhipicephalus microplus to different acaricides in tropical climates: Are the laboratory and field results related?

The aim of this study was therefore to investigate the relationship between laboratory (Larval Packet Test -LPT; Larval Immersion Test - LIT; Adult Immersion Test - AIT) and field studies using active ingredients or commercial formulations to control R. microplus in a tropical region. This comparative study was carried out with four populations of R.

Assessing the Links Between Artificial Intelligence and Precision Nutrition.

Purpose Of Review: To conduct an overview of the potentialities of artificial intelligence in precision nutrition.

Recent Findings: A keyword co-occurrence analysis of 654 studies on artificial intelligence (AI) and precision nutrition (PN) highlighted the potential of AI techniques like Random Forest and Gradient Boosting in improving personalized dietary recommendations. These methods address gastrointestinal symptoms, weight management, and cardiometabolic markers, especially when incorporating data on gut microbiota.

AI-Driven Innovations in Smart Multifunctional Nanocarriers for Drug and Gene Delivery: A Mini-Review.

The convergence of artificial intelligence (AI) and nanomedicine has revolutionized the design of smart multifunctional nanocarriers (SMNs) for drug and gene delivery, offering unprecedented precision, efficiency, and personalization in therapeutic applications. AI-driven approaches enhance the development of these nanocarriers by accelerating their design, optimizing drug loading and release kinetics, improving biocompatibility, and predicting interactions with biological barriers. This review explores the transformative role of AI in the fabrication and functionalization of SMNs, emphasizing its impact on overcoming challenges in targeted drug delivery, controlled release, and theranostics.

Bioengineered Tumor-Stroma Prostate Cancer In Vitro Models for Screening Therapeutics.

Cancer-associated fibroblasts are increasingly recognized to have a high impact on prostate tumor growth and drug resistance. Here, we bioengineered organotypic prostate cancer 3D in vitro models to better understand tumor-stroma interplay, the metabolomic profile underlying such interactions, and their impact on standard-of-care therapeutics performance. The assembly of robust and uniform spheroids was evaluated and compared in monotypic PC-3 and heterotypic microtumors comprised of either a healthy or malignant stroma and prostate cancer cells.

Scale of perception of family self-efficacy in home care for children on peritoneal dialysis.

Objectives: to validate an instrument for family self-efficacy perception in home care for children on peritoneal dialysis.

Methods: a methodological study. The theoretical framework was presented, conducted through a literature review, field research, item development, content validity by a committee of judges and semantic analysis with families.