Publications by authors named "L Ferini-Strambi"
Non-rapid eye movement (NREM) sleep parasomnias are abnormal motor and/or emotional behaviors originating from "deep" slow-wave sleep and with a multifactorial origin. The relationship between NREM parasomnias and psychopathology has been a topic of ongoing debate, but a comprehensive and systematic perspective has been lacking. This systematic review, conducted according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA-P) guidelines, aims to fill this gap in the literature.
View Article and Find Full Text PDFBackground: Patients with Parkinson's Disease (PD) frequently exhibit non-motor symptoms, particularly sleep disturbances. Sleep disorders in PD patients are intricately linked to the pathogenesis and progression of PD itself, exacerbating neurodegenerative processes and worsening patient quality of life.
Objectives: This review underscores the significance of sleep disorders in PD, highlighting their prevalence, impact on disease progression, and the bidirectional relationship between sleep disruption and neurodegeneration.
Article Synopsis
- The Coma Recovery Scale-revised (CRS-r) is the main tool for assessing patients with Disorders of Consciousness (DoCs), but it has a misdiagnosis rate of about 40%.
- Recent guidelines recommend adding neurophysiological measures, such as surface electromyography (sEMG), to improve these assessments.
- The STRIVEfc system was tested on DoCs patients, highlighting that it can reveal subtle muscular activities invisible to clinicians and helps improve diagnostic accuracy by providing additional information through an instrumented version of the CRS-r (ICRS-r).
Objective: This study aimed to investigate the prevalence of REM sleep behavior disorder (RBD) in patients with spontaneous intracranial hypotension (SIH) and longitudinally assess the effects of epidural blood patch (EBP) treatment on brainstem structures using a neuroimaging approach.
Methods: Twenty-two participants (10 SIH patients and 12 controls) underwent 3-Tesla Magnetic Resonance Imaging (MRI) scans. Midbrain and pons areas were measured on T1-weighted scans at baseline in both groups and three months after the first EBP in SIH patients to determine any MRI structural changes.