Publications by authors named "L FRANK"

Exosomes are a type of membrane vesicle secreted into the extracellular medium by most cell types. They have a great potential for clinical practice as noninvasive biomarkers for diagnosis of various diseases, prognosis, and monitoring of therapy, which stimulates the development of simple methods for isolating exosomes from biological fluids. A novel affine material based on aminosilanized superparamagnetic core‒shell nanoparticles for fast isolation of urinary exosomes is reported.

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Article Synopsis
  • Environmental DNA (eDNA) and environmental RNA (eRNA) metabarcoding are techniques used to assess biodiversity in aquatic environments, each with distinct strengths and limitations.
  • The study evaluated these methods in a Central European river, finding eRNA to detect more vertebrate species with a stronger local signature, while eDNA was more effective for invertebrates.
  • Both methods can provide valuable biodiversity data, but the choice between them depends on the specific research question being asked.
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Unlabelled: A biosensor based on field-effect transistors on silicon-on-insulator structures (SOI-biosensor) is a high-potential device for detection of biological molecules, for instance, such as troponin I; the biosensor allows conducting label-free real-time analysis. is the development of SOI-biosensor design for detection of acute myocardial infarction marker - troponin I. A notable feature of this design was the integration of two grounding electrodes directly onto the biosensor surface, which effectively nullified the static potential of the liquid sample and minimized physical breakdowns of biosensor elements.

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  • The study investigates how the brain represents and selects alternative possibilities during navigation in a complex environment, specifically focusing on the rat hippocampus.
  • Researchers found that rats represented multiple potential paths, both ahead and behind them, and that these representations changed based on the value of the rewards associated with different paths.
  • The findings suggest that the brain adjusts how it generates alternatives to support decision-making, helping animals adapt to their changing environment and cognitive requirements.
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Complementary and alternative medicines (CAMs) are frequently discussed by people with Inflammatory Bowel Disease (IBD). The aim of this study is to explore CAM use in Australians with IBD. This cross-sectional study was conducted via an anonymous online survey, predominantly distributed through IBD-specific social media accounts.

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