Publications by authors named "L F Zhandarova"

To ascertain precisely the gastric cancer stage is possible only during the operation. In many medical institutions the degree of local tumor proliferation and the level of its metastatic spread is assessed by a surgeon basing on his personal experience by the examination and palpation findings. Use of the intraoperative cytologic assay in surgical treatment of gastric cancer enables ascertaining the fact of tumor spread beyond the organ boundaries.

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Under examination were the features of life, labour, habits, inheritance pattern, a type of diet, the course of the disease in 440 gastric cancer patients. The most typical and frequently observed factors were singled out. The material obtained was processed by an electronic computer.

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The glucuronic acid level in the serum and urine, the diural excretion of estrogens and 17-KS with the urine, the activity of glucuronyltransferase are reported in 101 patients with benign and malignant tumors and in 22 healthy females. The decrease in the activity of glucurolytransferase and increase in the percentage of free (nonconjugated) estrogens in patients with malignant tumors of the mammary gland are noted, the analogous results were obtained in patients with benign tumors, but these are statistically insignificant. The decrease of the glucuronyltransferase activity is suggested to result in the development of relative hyperestrogen in normal total excretion.

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