Publications by authors named "L F Robbers"
A 62-year-old recreational cyclist presented with transient loss of consciousness and common electrocardiographic findings. Despite absence of left ventricular hypertrophy, multidisciplinary evaluation and a positive family history led to the diagnosis of non-classical Fabry disease. This case emphasizes the added value of multidisciplinary analysis of nonspecific findings to diagnose a rare disease.
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- - The study evaluates the effectiveness of quantitative perfusion cardiac magnetic resonance (QP-CMR) imaging in detecting significant coronary artery disease (CAD) in patients with a history of CAD and new chest pain, comparing it with visual assessment of stress perfusion CMR and quantitative PET imaging.
- - Involving 145 patients with prior heart issues, the research found QP-CMR's sensitivity at 66%, which is lower than PET at 80%, but its specificity is on par with both v-CMR and PET at about 60-63%.
- - Overall, the study concludes that QP-CMR's diagnostic performance is similar to that of both other imaging methods for identifying hemodynamically significant CAD, defined by fractional
Article Synopsis
- - The study analyzed the effects of prior coronary artery disease (CAD), sex, and age on optimal cutoffs for hyperemic myocardial blood flow (hMBF) and coronary flow reserve (CFR) in patients undergoing [O]HO PET and FFR testing.
- - Results showed that while cutoffs were mostly similar for those with and without prior CAD, females had higher hMBF cutoffs than males, though using sex-specific cutoffs reduced diagnostic accuracy.
- - Older patients (over 70 years) had lower hMBF and CFR cutoffs compared to younger groups, but these age-specific values did not enhance overall accuracy for detecting significant CAD compared to previously established thresholds.
Cardiac resynchronization therapy (CRT) is an established treatment for heart failure patients with left ventricular dysfunction and a left bundle branch block. However, its impact on right ventricular (RV) function remains uncertain. This cardiac magnetic resonance imaging study found that CRT did not improve RV volumes and function, and CRT-off during follow-up had an immediate detrimental effect on the RV, which may suggest potential unfavorable RV remodeling with RV pacing during CRT.
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