Publications by authors named "L F Palomino"
Background And Aims: Patients with very early-onset inflammatory bowel disease (VEO-IBD), with an age of onset < 6 years, can present with severe manifestations and may require biologic therapy. Infliximab and adalimumab are approved for induction and maintenance in pediatric IBD patients but are licensed only above the age of 6 years. Effectiveness and safety data on adalimumab in this patient population are lacking.
View Article and Find Full Text PDFSpontaneous cutaneous-parotid fistula of the cheek caused by sialolithiasis in a child: a case report.
Eur Arch Otorhinolaryngol
January 2025
Introduction: Cheek fistulas of salivary origin in children are very rare, predominantly of congenital or traumatic origin but rarely caused by parotid sialolithiasis given its low prevalence in paediatric populations.
Case Presentation: A 3-year-old child with no history other than substantial left-cheek swelling for 2 months was referred. We identified a cutaneous fistula with seropurulent discharge.
Article Synopsis
- The study assessed how being overweight or obese affects treatment response and relapse rates in children with inflammatory bowel disease (IBD) undergoing anti-TNF therapy.
- Conducted across 22 centers in 14 countries, it involved 637 children, with a comparison between those who were overweight/obese and those of normal weight.
- Findings showed no difference in loss of response to treatment initially, but overweight/obese children had higher relapse rates by the end of follow-up, indicating a potential long-term risk associated with their weight status.
Article Synopsis
- Pediatric inflammatory bowel disease (PIBD) significantly affects family dynamics and caregiver work productivity, leading to economic strain on families.
- A multicenter study involving 370 parents of PIBD patients aged 10-18 revealed a 22.9% unemployment rate among caregivers, notably higher for mothers at 30.7%, with absenteeism and presenteeism further complicating work situations.
- The research highlights the need for targeted support and policy improvements to reduce the socioeconomic impact on families caring for children with PIBD.