Publications by authors named "L F Olsson"
Novel species of fungi described in this study include those from various countries as follows: , from accumulated snow sediment sample. , on leaf spots of . , on submerged decaying wood in sea water, on , as endophyte from healthy leaves of .
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- Obesity during mid-life is linked to a higher risk of renal cell carcinoma (RCC), but obese patients diagnosed with RCC tend to have better survival rates, highlighting an "obesity paradox."
- 334 patients with localized RCC were studied regarding their pre- and post-diagnosis weight changes, revealing an average weight loss of 1.45 kg in the two years leading up to diagnosis.
- Non-obese patients and those with more advanced tumors experienced greater weight loss prior to diagnosis, and a portion of that weight was regained within two years after diagnosis, indicating disease-related weight loss patterns that may explain the obesity paradox.
The use of mixed cultures in gas fermentations could reduce operating costs in the production of liquid chemicals such as alcohols or carboxylic acids. However, directing reducing equivalents towards the desired products presents the challenge of co-existing competing pathways. In this study, two trickle bed reactors were operated at acetogenic and chain elongating conditions to explore the fate of electron equivalents (ethanol, H, and CO) and test pH oscillations as a strategy to target chain-elongated products.
View Article and Find Full Text PDFMetabolic dysfunction-associated steatotic liver disease (MASLD) exhibits considerable variability in clinical outcomes. Identifying specific phenotypic profiles within MASLD is essential for developing targeted therapeutic strategies. Here we investigated the heterogeneity of MASLD using partitioning around medoids clustering based on six simple clinical variables in a cohort of 1,389 individuals living with obesity.
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- Researchers focused on breast cancer subtypes Luminal A and Luminal B, using machine learning to analyze H&E images, aiming to identify tumor characteristics linked to higher recurrence risks.
- The study involved training models on segmented images of tumors, finding that an image-based protocol effectively predicted recurrence times, comparable to traditional genomic testing methods (PAM50).
- Results indicated that while adjusting for tumor grade didn't significantly improve subtype prediction, the image analysis provided a viable alternative in identifying patients in need of genomic testing, potentially increasing testing rates among ER+/HER2-patients.