Publications by authors named "L F Macedo Mota"

Objectives: To compare the impact of COVID-19 on the clinical status and psychological distress of patients with immune-mediated rheumatic disease (IMRD) caused by SARS-CoV-2 infection with that of noninfected IMRD controls during a 6-month follow-up period.

Methods: The ReumaCoV Brazil is a longitudinal study designed to follow IMRD patients for 6 months after COVID-19 (patients) compared with IMRD patients without COVID-19 (controls). Clinical data, disease activity measurements and current treatments regarding IMRD and COVID-19 outcomes were evaluated in all patients.

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Cellulose-based materials are promising adsorbents for pollutants and other classes of compounds. Here, we report the preparation of hydrogels via chemical cross-linking of microcrystalline cellulose oxidized by the 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO). The cross-linking process was carried out in the presence of modifiers such as β-cyclodextrin in order to insert hydrophobic cavities or κ-carrageenan due to the presence of negative charges along the molecular chains.

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This study aimed to identify mRNA isoforms that were expressed differently in the muscle tissue of Nellore cattle based on their intramuscular fatty acid profile. Forty-eight young bulls were used to quantify beef fatty acids (FA) and perform RNA sequencing analysis. The young bulls were divided into three different groups based on quantifying FA using k-means analysis.

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Traditionally, control of coffee plant bacterial halo blight (BHB) caused by the phytopathogen Pseudomonas coronafaciens pv. garcae (Pcg) involves frequent spraying of coffee plantations with non-environmentally friendly and potentially bacterial resistance-promoting copper products or with kasugamycin hydrochloride. In this study we report a leap forward in the quest for a new ecofriendly approach, characterizing (both physicochemically and biologically) and testing both in vitro and ex vivo a new lytic phage for Pcg.

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Article Synopsis
  • RF titers are significant in the pathophysiology of rheumatoid arthritis (RA) and vary in their clinical impact, with high RF titers linked to poorer health outcomes.
  • A study with 1,097 RA adults found a substantial portion had positive RF, with high titers prevalent, and identified associations of high RF with factors such as tobacco use and higher body mass index.
  • High RF levels correlated with increased disease activity, reduced functional capacity, and greater use of corticosteroids and biological drugs, indicating a need for careful monitoring in RA patients.
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