Publications by authors named "L F Hayashi"
Situs inversus totalis in an asymptomatic adolescent - importance of patient education: A case report.
World J Clin Pediatr
December 2023
Background: Situs inversus totalis (SIT) may be an incidental finding in asymptomatic children. Patients may not understand the implications of this condition and the importance of relaying the diagnosis to their healthcare providers.
Case Summary: We report an asymptomatic seventeen-year-old adolescent with previously-diagnosed SIT who presented for a routine well-child visit.
Adaptation and Validation of the International Pelvic Pain Society's Quality of Life Questionnaire in Portuguese.
Rev Bras Ginecol Obstet
October 2023
Objective: In the present study, our aim was to translate, adapt, and validate the Pelvic Health History Form (a quality of life [QoL] questionnaire) of the International Pelvic Pain Society (IPPS) from English to Portuguese.
Methods: The study was approved by the Ethics and Research Committee (CEP, in the Portuguese acronym) and the IPPS. The "Transcultural Adaptation" method comprised 5 stages: translation, synthesis, backtranslation, expert review, and pretest.
Article Synopsis
- Prior studies suggest that eating protein-rich foods and non-starchy vegetables before carbohydrates can lower glucose levels in people with prediabetes or type 2 diabetes.
- This study examined the effects of a carbohydrate-last food order intervention on weight, glucose tolerance, and diet quality in 45 adults with prediabetes over 16 weeks.
- Results indicated that participants who followed the carbohydrate-last order lost more weight and improved their diet quality by increasing protein and vegetable intake, making this approach a feasible strategy for enhancing nutrition in individuals with prediabetes.
Article Synopsis
- The study aimed to assess how often the 1-mg overnight dexamethasone suppression test (DST) yielded invalid results in patients being evaluated for conditions like Cushing syndrome.
- Among 1,300 tests analyzed, 146 (11.2%) were deemed invalid, primarily due to low serum dexamethasone levels influenced by factors like medication interference and patient adherence issues.
- The findings highlight that proper medication intake and recognizing the effects of certain drugs on test results are crucial for accurate DST interpretation, suggesting simultaneous measurement of serum cortisol and dexamethasone could improve test reliability.
Sound-including music and noise-can relieve pain in humans, but the underlying neural mechanisms remain unknown. We discovered that analgesic effects of sound depended on a low (5-decibel) signal-to-noise ratio (SNR) relative to ambient noise in mice. Viral tracing, microendoscopic calcium imaging, and multitetrode recordings in freely moving mice showed that low-SNR sounds inhibited glutamatergic inputs from the auditory cortex (ACx) to the thalamic posterior (PO) and ventral posterior (VP) nuclei.
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