Publications by authors named "L F Bouzas"
Background: Childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL) has been associated with early-life exposures, including birth by cesarean section (C-section), and a deficit of social exposure (first child). These exposures as proxies for microbiome acquisition in infancy are essential to prime the immune system and restrain later dysregulated immune responses that can trigger ALL in susceptible individuals. We tested risk factors pertaining to immune stimulation that may impact BCP-ALL development.
View Article and Find Full Text PDFGVHD treatment with extracorporeal photopheresis in Brazil: a national survey.
Hematol Transfus Cell Ther
January 2022
Article Synopsis
- - The study examined the link between cardiovascular events (CVE) and bronchiectasis exacerbations, showing that the risk of CVE increases during and after these episodes.
- - Analyzed patient data from 250 individuals, the results revealed that 29.6% experienced a CVE during follow-up, and 37.2% died, with certain factors like age and COPD heightening the risk of CVE.
- - The findings suggest that demographic factors and existing health conditions are significant predictors of CVE following bronchiectasis exacerbations, which negatively impacts long-term survival outcomes.
Article Synopsis
- Endothelial injury plays a significant role in worsening outcomes for respiratory infections, including COVID-19, but is not well-understood.
- A study analyzed levels of proadrenomedullin (proADM) and proendothelin in COVID-19 patients, finding that higher baseline levels linked to severe cases and ICU admissions.
- Elevated proADM or proendothelin levels on the first day of hospitalization correlated with higher in-hospital mortality rates and ongoing health issues after discharge.