Publications by authors named "L Espinoza-Hernandez"
Evidence of spatial clustering of childhood acute lymphoblastic leukemia cases in Greater Mexico City: report from the Mexican Inter-Institutional Group for the identification of the causes of childhood leukemia.
Front Oncol
February 2024
Background: A heterogeneous geographic distribution of childhood acute lymphoblastic leukemia (ALL) cases has been described, possibly, related to the presence of different environmental factors. The aim of the present study was to explore the geographical distribution of childhood ALL cases in Greater Mexico City (GMC).
Methods: A population-based case-control study was conducted.
Article Synopsis
- Childhood cancer, especially acute leukemia, is the leading cause of disease-related deaths in children aged 5-14 in Mexico, highlighting the need for understanding dietary influences during pregnancy.
- A hospital-based study compared dietary habits of mothers of 109 infants with acute leukemia to those of 152 healthy controls, showing that overall maternal dietary patterns can significantly impact infant health.
- The findings indicate that a "Balanced & Vegetable-Rich" diet during pregnancy is associated with a lower risk of acute leukemia in infants, particularly for mothers of girls, emphasizing the role of maternal nutrition in disease prevention.
Reply to the Editor regarding Lucas da Silva, master's student letter-reference manuscript #YCLNU-D-23-01654 Pilot study on the effect of supplementation with long-chain ω-3 polyunsaturated fatty acids on body composition in children with acute lymphoblastic leukemia: Randomized clinical trial.
Clin Nutr
December 2023
Introduction: Maternal dietary consumption during pregnancy has been inconclusively associated with acute leukemia (AL) in infants, probably because epidemiological evidence has emerged mainly from the analysis of one-by-one nutrient, which is not a real-life scenario. Our objective was to evaluate the association between AL in Mexican children under 2 years of age and their mothers' nutrients concomitant intake during pregnancy, as well as to explore whether there are differences between girls and boys.
Methods: We conducted a study of 110 cases of AL and 252 hospital-based controls in the Mexico City Metropolitan area from 2010 to 2019.
Pilot study on the effect of supplementation with long-chain ω-3 polyunsaturated fatty acids on body composition in children with acute lymphoblastic leukemia: randomized clinical trial.
Clin Nutr
September 2023
Background: N-3 polyunsaturated fatty acids (LCPUFA-ω3), particularly docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) might have beneficial effects on lean mass and fat mass synthesis.
Objective: To investigate the effect of LCPUFA-ω3 supplementation on body composition changes in children with acute lymphoblastic leukemia (ALL) at remission and three months (3 mo) after supplementation.
Methods: This randomized controlled trial enrolled 72 children (3-13 y) with newly diagnosed ALL (placebo group [500 mg sunflower oil]: 36 patients; LCPUFA-ω3 group [225 mg DHA, 45 mg EPA]: 36 patients).