Co-expression and impact of prostate specific membrane antigen and prostate specific antigen in prostatic pathologies.

Background: The present study was undertaken to relate the co-expression of prostate-associated antigens, PSMA and PSA, with the degree of vascularization in normal and pathologic (hyperplasia and cancer) prostate tissues to elucidate their possible role in tumor progression.

Methods: The study was carried out in 6 normal, 44 benign prostatic hyperplastic and 39 cancerous human prostates. Immunohistochemical analysis were performed using the monoclonal antibody CD34 to determine the angiogenic activity, and the monoclonal antibodies 3E6 and ER-PR8 to assess PSMA and PSA expression, respectively.

[Effect of hexachlorobenzene on some male reproductive parameters in Meriones unguiculatus].

Organochlorine pesticides are known to cause disturbances in many physiological functions. The effects of in vivo administered hexachlorobenzene (HCB) on the male testicular function were studied in Meriones unguiculatus. Three groups of sexually mature meriones were orally exposed to 1.

[Toxicity of hexachlorobenzene in Meriones unguiculatus: effects on thyroid and liver].

The effect of in vivo administered hexachlorobenzene (HCB) on liver and thyroid was studied on Meriones unguiculatus. HCB (1.6, 4, and 16 mg/kg of body weight) has been administered orally to meriones for 30 days.

[Extrapulmonary tuberculosis in Tunisia. Report of 830 cases. Experience of the Anatomic Pathology Laboratory of the Rabta Hospital].

We present the experience of pathological laboratory of la Rabta hospital in extra-pulmonary tuberculosis. We report an epidemiologic retrospective study of 830 cases occurring in our service over a period of 10 years from 1991 to 2000 and diagnosed by histopathological examination. Various epidemiological, clinical, pathological and diagnostic aspects are discussed.