Longitudinal Measurements of FGF23, Sarcopenia, Frailty and Fracture in Older Community Dwelling Women.

Background: FGF23 has been associated with frailty and functional performance in older individuals, but the association to sarcopenia is unknown.

Objectives: To investigate the association between FGF23, frailty, sarcopenia and fractures in older community dwelling women.

Design: Prospective longitudinal cohort study.

Patient-related outcome, fracture displacement and bone mineral density following distal radius fracture in young and older men.

Background: Distal radius fractures can adversely affect wrist function; for men with this fracture, the role played by fracture severity, age and osteoporosis on fracture outcome has not been sufficiently studied.

Objective: To describe patient-reported outcome and the association with bone integrity, fracture severity and future fracture risk among young and older men with distal radius fracture.

Methods: This prospective study includes 133 men with acute distal radius fracture, mean age 54 (range 21-88), who were followed for 12 months.

High Luteinizing Hormone and Lower Levels of Sex Hormones in Younger Men With Distal Radius Fracture.

This study investigates the sex steroid hormone profile in younger men with distal radius fracture (DRF) to elucidate if this could explain the low bone density and osteoporosis previously observed. In a case-control study, 73 men with DRF (mean age 38 ± 9 years; range, 20-51) was compared with 194 age-matched, population controls. Performed assays: total testosterone (TT), calculated free testosterone (cFT), luteinizing hormone (LH), follicle-stimulating hormone (FSH), sex hormone-binding globulin (SHBG), and total estradiol (E2).

Disability and Pain are the Best Predictors of Sick Leave After a Distal Radius Fracture in Men.

Purpose Distal radius fracture often compromises working ability, but clinical implications are less studied in men due to its lower incidence. This study therefore describes sick leave in men with distal radius fracture, specifically exploring the impact of patient- and fracture-related factors. Methods Professionally active men aged 20-65 with distal radius fracture were followed prospectively for 1-year (n = 88).

Low bone mineral density is associated with hypogonadism and cranial irradiation in male childhood cancer survivors.

Unlabelled: We investigated if bone mineral density was related to testosterone deficiency and/or previous cancer treatment in men who were childhood cancer survivors. Men with untreated testosterone deficiency or previous treatment with cranial irradiation were at increased risk of impaired bone health. Prevention of osteoporosis should be considered in their follow-up.