Dydrogesterone is an eligible tool to suppress LH surge in assisted reproduction technologies (ART) cycles.

Objective: To evaluate Dydrogesterone's effectiveness in PPOS protocols for IVF/ICSI or oocyte cryopreservation, focusing on LH surge suppression and metaphase II oocyte yield.

Methods: A retrospective, comparative, single-center study of 550 IVF/ICSI and 186 oocyte cryopreservation cycles was conducted from January 2018 to December 2020. Exclusion criteria included endometriosis, previous ovarian surgery, ovarian insufficiency, and abnormal FSH/LH levels.

Notch1 Signalling Is Downregulated by Aerobic Exercise, Leading to Improvement of Hepatic Metabolism in Obese Mice.

Background And Aims: Notch1 protein plays a significant role in hepatic metabolism, as evidenced by its correlation with insulin resistance in the livers of obese individuals, making it an intriguing research target. Therefore, this study aims to investigate the impact of aerobic exercise on Notch1 pathways in the hepatic tissue of obese mice and its role in controlling hepatic metabolism.

Methods: Therefore, we conducted a cross-sectional study utilising liver biopsies from lean and obese humans, as well as an intervention study involving mice subjected to a high-fat diet.

Nutritional Factors and Food and Nutrition Insecurity in Patients with Tuberculosis.

: Brazil has a high incidence of new tuberculosis cases influenced by socioeconomic factors. Inadequate housing, limited access to health services, and insufficient food increase vulnerability to the disease. This study aimed to identify sociodemographic, nutritional, and anthropometric factors associated with active pulmonary tuberculosis.

Assessment of Sustainable Ethanolamine-Based Protic Ionic Liquids with Varied Carboxylic Acid Chains as Corrosion Inhibitors for Carbon Steel in Saline Environments.

The inhibitory performance of three distinct protic ionic liquids (PILs), namely, 2-hydroxyethyl ammonium formate (PIL 01), 2-hydroxyethyl ammonium propionate (PIL 02), and 2-hydroxyethyl ammonium pentanoate (PIL 03), was evaluated to determine their suitability as eco-friendly corrosion inhibitors for carbon steel (ASTM A36) in a 3.5 wt. % NaCl aerated neutral electrolyte solution.

The Biflavonoid Agathisflavone Regulates Microglial and Astrocytic Inflammatory Profiles via Glucocorticoid Receptor.

Nuclear receptors such as glucocorticoid receptors (GRs) are transcription factors with prominent regulatory effects on neuroinflammation. Agathisflavone is a biflavonoid that demonstrates neurogenic, neuroprotective, anti-inflammatory, antioxidant, and pro-myelinogenic effects in vitro. This study investigated whether the control of glial reactivity by agathisflavone is mediated by GRs.