Technology and Dementia Preconference.

Background: Chronic stress promotes life-long risk for neuropsychiatric decline by increasing neuroinflammation and disrupting synaptic health and plasticity. Our lab and others have recently demonstrated that non-invasive gamma sensory stimulation (flicker) modulates immune signaling, restores microglial function, and improves cognitive performance in mouse models of Alzheimer's disease (AD). However, no research to date has studied the effects of flicker in the context of stress.

Urinary Metabolite Profiles of Participants with Overweight and Obesity Prescribed a Weight Loss High Fruit and Vegetable Diet: A Single Arm Intervention Study.

Background/objectives: Thus far, no studies have examined the relationship between fruit and vegetable (F and V) intake, urinary metabolite quantities, and weight change. Therefore, the aim of the current study was to explore changes in urinary metabolomic profiles during and after a 10-week weight loss intervention where participants were prescribed a high F and V diet (7 servings daily).

Methods: Adults with overweight and obesity ( = 34) received medical nutrition therapy counselling to increase their F and V intakes to national targets (7 servings a day).

YAP regulates periosteal expansion in fracture repair.

Bone fracture repair initiates by periosteal expansion. The periosteum is typically quiescent, but upon fracture, periosteal cells proliferate and contribute to bone fracture repair. The expansion of the periosteum is regulated by gene transcription; however, the molecular mechanisms behind periosteal expansion are unclear.

De novo generation of colorectal patient educational materials using large language models: Prompt engineering key to improved readability.

Background: Improving patient education has been shown to improve clinical outcomes and reduce disparities, though such efforts can be labor intensive. Large language models may serve as an accessible method to improve patient educational material. The aim of this study was to compare readability between existing educational materials and those generated by large language models.

Technology-Related Safety Strategies Among College Student Survivors Using Campus-Based Advocacy Services.

Technology can be leveraged as a tool by perpetrators of interpersonal violence, which requires survivors to consider digital platforms as part of their safety planning processes. To explore how survivors are addressing these safety concerns, we performed secondary, qualitative content analysis of semistructured interviews with college students who used campus-based advocacy services for interpersonal violence. Participants described an array of technology-related safety strategies they implemented to protect themselves across multiple types of digital technologies.