Publications by authors named "L E Stoica"
SYSTEMIC INFLAMMATORY MARKERS - PROGNOSTIC VALUE IN OVARIAN CANCER.
Acta Endocrinol (Buchar)
January 2025
Background: Chronic inflammation is associated with different cancers, and is identified as a key pathogenic mechanism in ovarian cancer. The purpose of our study was to evaluate systemic inflammation markers, as predictive and prognostic factors, in ovarian cancer patients with initial surgical treatment.
Subjects And Methods: We performed a retrospective study on 60 ovarian cancer patients with primary cytoreduction surgery, between 2010-2018, with a follow-up period of at least one year.
: Ongoing challenges in epilepsy therapy warrant research on alternative treatments that offer improved efficacy and reduced side effects. Designed to enhance mitochondrial targeting and increase bioavailability, mitocurcumin (MitoCur) was evaluated for the first time as an antiepileptic agent, with curcumin (Cur) and sodium valproate (VPA), a standard antiepileptic drug, included for comparison. This study investigated the effects on seizure onset, severity, and progression in a zebrafish model of pentylenetetrazole (PTZ)-induced seizures and measured the concentrations of the compounds in brain tissue.
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- Sports anxiety can hinder athletes' performance and reduce their overall life satisfaction.
- The study found that positive thinking skills are linked to higher life satisfaction and can help alleviate sport anxiety.
- Encouraging the development of positive thinking skills in training programs may improve athletes' mental wellbeing and performance outcomes.
Article Synopsis
- The study involved 54 psoriasis (PsO) patients and 40 control subjects to investigate the prevalence of metabolic syndrome (MetS) and its link to subclinical atherosclerosis, assessed through carotid ultrasound.
- Results showed that 64.81% of PsO patients had MetS compared to only 27.5% of control patients, indicating a significant difference in metabolic health between the two groups.
- The findings also revealed a higher incidence of carotid plaque and increased intima-media thickness (IMT) in PsO patients with MetS, suggesting a strong correlation between MetS, psoriasis, and an elevated risk of cardiovascular issues.
The present study is aimed at assessing the presence and prevalence of subclinical entheseal changes in Psoriasis (PsO) patients using musculoskeletal ultrasonography (US), conjoined with the analysis of possible differences in terms of demographic, clinical, or biological features. We carried out an observational study on 54 patients with PsO and 40 controls. Subclinical enthesopathy, according to OMERACT definitions, was identified in 20 of the psoriasis patients (37.
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