Publications by authors named "L E Quint"
Article Synopsis
- Mature blood cells develop from hematopoietic stem cells in bone marrow through a differentiation process that may be either organized (instructive) or random (stochastic).
- Research using single-cell transcriptomic data showed variability in gene expression during blood cell differentiation, with notable peaks in variability at certain stages across different cell lineages.
- Findings suggest that hematopoietic differentiation should be viewed as a dynamic stochastic process characterized by periods of uncertainty, supporting the idea that differentiation involves significant cell-to-cell variability.
Medical errors may lead to patient harm and may also have a devastating effect on medical providers, who may suffer from guilt and the personal impact of a given error (second victim experience). While it is important to recognize and remedy errors, it should be done in a way that leads to long-standing practice improvement and focuses on systems-level opportunities rather than in a punitive fashion. Traditional peer review systems are score based and have some undesirable attributes.
View Article and Find Full Text PDFErdheim-Chester Disease with Pulmonary and Osseous Involvement.
Radiol Cardiothorac Imaging
August 2021
Background And Aims: To investigate effectiveness and safety of teriflunomide (14 mg once daily) in association with age and pre-treatment in unselected MS patients.
Methods: Prespecified analysis of a non-interventional, prospective, real-world study in Germany.
Results: A total of 558 (49.