Publications by authors named "L E Probst"
Article Synopsis
- The study investigates how Matrix Support (MS) affects integration between Primary Health Care (PHC) and Dental Specialty Centers (CEOs) in Brazil.
- Findings reveal that nearly half of the CEOs lack collaborative therapeutic projects with PHC oral health teams, which is linked to various factors like poor case discussions and absence of joint educational activities.
- The conclusion emphasizes that individual practices within CEOs play a more significant role in the integration issues than broader contextual factors from local municipalities.
Article Synopsis
- Monkeypox virus (MPXV) causes mpox, a pox-like disease, and since May 2022, there's been a notable outbreak with increased human-to-human transmission outside its usual regions.
- Whole genome sequencing (WGS) is essential for tracking MPXV evolution, but existing methods face challenges related to mutations and varied viral clades.
- A new isothermal WGS method using Phi29 DNA polymerase achieves high genome coverage (88% to 100%) from both DNA and clinical samples and is effective for monitoring MPXV outbreaks in standard laboratories.
Background: The reward-regulatory properties of GLP-1 are attracting increasing interest. Animal studies show that GLP-1 receptor agonists not only reduce consumption of addictive substances, but also influence sexual behaviour. We aimed to investigate the effect of dulaglutide versus placebo on sexual desire in humans.
View Article and Find Full Text PDFThe dairy industry has been expanding significantly recently, which has prompted the improvement and adoption of increasingly digital dairy recording tools with cutting-edge technology. The study aimed to identify smallholder dairy farmers' recording tools in developing countries. The study presents the results of an extensive literature review conducted using electronic journal databases.
View Article and Find Full Text PDFEfficacy and safety of onasemnogene abeparvovec for the treatment of patients with spinal muscular atrophy type 1: A systematic review with meta-analysis.
PLoS One
May 2024
Background: Onasemnogene abeparvovec has been approved for the treatment of spinal muscular atrophy 5q type 1 in several countries, which calls for an independent assessment of the evidence regarding efficacy and safety.
Objective: Conduct a meta-analysis to assess the efficacy and safety of onasemnogene abeparvovec in patients diagnosed with SMA type 1, based on the available evidence.
Methods: This article results from searches conducted on databases up to November 2022.