Publications by authors named "L E Politi"
Article Synopsis
- This study examines the long-term effects of elective Endovascular Aneurysm Repair (EVAR) on the common iliac arteries (CIAs) using various modern aortic endografts in a cohort of 168 patients.* -
- Over a 5-year follow-up, significant increases in the diameter (11.7% at 24 months, 22.8% at 60 months) and length of CIAs were observed, indicating a concerning progression of aneurysmal disease.* -
- The research found that increased CIA dilatation significantly predicted long-term EVAR failures, highlighting the need for comprehensive follow-up to ensure ongoing effectiveness of the procedure.*
Radiomics features (RFs) serve as quantitative metrics to characterize shape, density/intensity, and texture patterns in radiological images. Despite their promise, RFs exhibit reproducibility challenges across acquisition settings, thus limiting implementation into clinical practice. In this investigation, we evaluate the effects of different CT scanners and CT acquisition protocols (KV, mA, field-of-view, and reconstruction kernel settings) on RFs extracted from lumbar vertebrae of a cadaveric trunk.
View Article and Find Full Text PDFActivation of retinoid X receptors protects retinal neurons and pigment epithelial cells from BMAA-induced death.
Biochim Biophys Acta Mol Cell Res
December 2024
Exposure to the non-protein amino acid cyanotoxin β-N-methylamino-L-alanine (BMAA), released by cyanobacteria found in many water reservoirs has been associated with neurodegenerative diseases. We previously demonstrated that BMAA induced cell death in both retina photoreceptors (PHRs) and amacrine neurons by triggering different molecular pathways, as activation of NMDA receptors and formation of carbamate-adducts was only observed in amacrine cell death. We established that activation of Retinoid X Receptors (RXR) protects retinal cells, including retina pigment epithelial (RPE) cells from oxidative stress-induced apoptosis.
View Article and Find Full Text PDFBackground: After approval for clinical use in 2017, early investigations of ultra-high-field abdominal magnetic resonance imaging (MRI) have demonstrated its feasibility as well as diagnostic capabilities in neuroimaging. However, there are no to few systematic reviews covering the entirety of its neurosurgical applications as well as the trends in the literature with regard to the aforementioned application.
Aim: To assess the impact of 7-Tesla MRI (7T MRI) on neurosurgery, focusing on its applications in diagnosis, treatment planning, and postoperative assessment, and to systematically analyze and identify patterns and trends in the existing literature related to the utilization of 7T MRI in neurosurgical contexts.