Publications by authors named "L E Lopes-Santos"

Article Synopsis
  • - This study explored neurological effects of COVID-19 by analyzing cerebral glycolytic metabolism in patients with mild long COVID cognitive symptoms and comparing them to healthy volunteers using PET/CT scans.
  • - Despite not finding significant differences in glucose metabolism between the two groups, researchers noted hypometabolism in 15 brain regions and hypermetabolism in 11 regions in the mild COVID group, particularly in areas related to cognitive function and emotional regulation.
  • - The authors suggest that future research should involve larger samples and consider correlating these metabolic changes with cognitive and psychiatric assessments to better understand the potential neurological impacts of COVID-19.
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The global impact of the Coronavirus Disease (COVID-19) pandemic has extended beyond physical health, leading to widespread mental health issues. Beyond respiratory symptoms, there is a growing concern about long-term cognitive effects, particularly in individuals who experienced mild cases of the infection. We aimed to investigate the neuropsychological aspects of long-term COVID-19 in non-hospitalized adults compared with a control group.

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Objective: People with epilepsy are at an increased risk of experiencing executive dysfunction, particularly those with frontal lobe epilepsy (FLE). The literature has also demonstrated alterations in executive functioning (EF) in patients with temporal lobe epilepsy (TLE). However, few studies have examined the neuropsychological profile of posterior cortex epilepsy (PCE), and little attention has been given to cognitive impairments in the pediatric population with PCE.

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Oral cancer refers to malignant tumors, of which 90% are squamous cell carcinomas (OSCCs). These malignancies exhibit rapid progression, poor prognosis, and often mutilating therapeutical approaches. The determination of a prophylactic and/or therapeutic antitumor role of the polyphenolic extract would be relevant in developing new tools for prevention and treatment.

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Oral cavity cancer is still an important public health problem throughout the world. Oral squamous cell carcinomas (OSCCs) can be quite aggressive and metastatic, with a low survival rate and poor prognosis. However, this is usually related to the clinical stage and histological grade, and molecular prognostic markers for clinical practice are yet to be defined.

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