Publications by authors named "L E Karran"
Article Synopsis
- The study investigated the trend of alcohol-related acute pancreatitis (AP) admissions during the initial COVID-19 lockdown in the UK, noting a notable rise in first-time admissions in 2020 compared to previous years.
- The highest total admissions occurred during March-May 2020, coinciding with increased alcohol consumption as restrictions took effect, while admissions declined by 38.89% once restrictions eased.
- Despite the surge in admissions during the lockdown, the median length of hospital stay remained consistent across the years studied, indicating no change in severity or duration of care for patients.
Background: Prolyl hydroxylation is a post-translational modification that affects the structure, stability and function of proteins including collagen by catalysing hydroxylation of proline to hydroxyproline through action of collagen prolyl hydroxylases3 (C-P3H) and 4 (C-P4H). Three C-P3Hs (nomenclature was amended according to approval by the HGNC symbols and names at http://www.genenames.
View Article and Find Full Text PDFThe Polo-like kinases (Plks) are a highly conserved family of protein kinases that function in regulation of cell cycle and DNA damage-induced checkpoints. Evidence of a tumor suppressor function for the Plks in human neoplasia is lacking. Here, we report that Snk/Plk2 is transcriptionally down-regulated in B-cell neoplasms.
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