Introduction: Current guidelines recommend extended venous thromboembolism (VTE) prophylaxis after colorectal surgery for cancer, but adherence to these guidelines has been low. Moreover, its effectiveness has not been evaluated using real-world data.
Methods: We retrospectively analyzed a random 25% sample of the 2009-2022 IQVIA Pharmetrics® Plus for Academics (IPPA) database, an administrative claims database representative of the commercially insured population of the United States.
Phenotypic data are critical for understanding biological mechanisms and consequences of genomic variation, and are pivotal for clinical use cases such as disease diagnostics and treatment development. For over a century, vast quantities of phenotype data have been collected in many different contexts covering a variety of organisms. The emerging field of phenomics focuses on integrating and interpreting these data to inform biological hypotheses.
View Article and Find Full Text PDFBackground: Adults with learning disabilities face increased risks of unhealthy lifestyle behaviours, including alcohol consumption, smoking, low physical activity, sedentary behaviour and poor diet. Lifestyle modification interventions that target health-risk behaviours can prevent or reduce their negative effects. The goal of this project was to investigate the effectiveness and underlying mechanisms of lifestyle modification interventions in adults with learning disabilities.
View Article and Find Full Text PDFObjective: Left subclavian artery (LSA) revascularization has been recommended for thoracic endovascular aortic repairs (TEVAR) that require LSA coverage to achieve adequate seal. The aim of this study is to evaluate the comparative effectiveness of endovascular techniques versus surgical methods for LSA revascularization.
Methods: The vascular quality initiative (VQI) was queried for patients undergoing TEVAR involving the arch from August 2014 to November 2023.