Publications by authors named "L E Grzeskowiak"

Context: Women achieving pregnancy with infertility treatment may be at increased risk of stillbirth and neonatal death.

Objective: To assess associations between clomiphene citrate (CC) use and perinatal death.

Design: Whole of population data linkage cohort.

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Background: Disease modifying treatments (DMTs) for multiple sclerosis (MS) have varying levels of teratogenic potential, but whether this influences DMT prescribing patterns by sex or concurrent use of hormonal contraception in women is unknown. This study aimed to examine patterns in dispensing of DMTs in women and men with MS, and hormonal long-acting reversible contraceptive (LARC) overlap at DMT initiation among women.

Methods: Population cohort study using 10% random sample of the Australian Pharmaceutical Benefits Scheme dispensing data (2007-2021).

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Article Synopsis
  • - The study investigated how different diets (hay vs. sugar beet pulp) and grinding sizes (fine vs. coarse) during sow gestation and lactation affect stress and immune markers in both sows and their piglets, as well as the impact of weaning age (conventional vs. late).
  • - Salivary markers such as chromogranin A (CgA), alpha-amylase, and oxytocin were notably influenced by diet and weaning age, with specific increases observed in sows and piglets fed certain types of fiber at various weaning stages.
  • - Overall, the findings indicate that dietary fiber type, weaning age, and grinding size significantly influence stress and immune responses in pigs,
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Background: Lactation is associated with long-term reduced risk of breast cancer. However, there is a transient increased risk of breast cancer in the 5 to 10 years postpartum and this is associated with a high incidence of metastasis and mortality. Breastmilk is a physiological fluid secreted by the mammary glands intimately connected with breast cells and the microenvironment that may affect postpartum breast cancer development and progression.

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Objectives: To examine patterns in the dispensing of category X medications (Therapeutic Goods Administration categorisation system for prescribing medicines in pregnancy) to women aged 15-49 years in Australia during 2008-2021, and patterns of concurrent use of hormonal long-acting reversible contraception (LARC) and other hormonal contraception.

Study Design: Retrospective cohort study; analysis of 10% random sample of national Pharmaceutical Benefits Scheme dispensing data.

Participants, Setting: Women aged 15-49 years dispensed category X medications, Australia, 1 January 2013 - 31 December 2021.

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