Experimental study of the effects of radiofrequency electromagnetic fields on animals with soft tissue wounds.

The effect of radio frequency electromagnetic fields (RF EMF) was studied on Wistar rats with excised full-thickness dermal wounds in the interscapular region. The wounded regions of experimental animals were subjected to EMF for 30 min daily during the first 5 days after wound infliction. Control animals received no treatment.

Biochemical characterization of connective tissue reaction to synthetic polymer implants.

The present review is concerned with the significance and prospects of the use of biochemical methods to characterize connective tissue reaction to implanted synthetic polymer materials. The necessity of carrying out complex quantitative analysis of capsules developing around the implants in order to elucidate qualitative peculiarities of the reaction and to objectify the assessment of the reactogeneity of the material is emphasized.

[Silatranes as stimulators of the development of granulation tissue].

Experiments on rats were made to study the effect of I-(chloromethyl) silatrane and I- (ethoxy) silatrane and that of triethanolamine and chloromethyl triethoxysilane on biochemical parameters of granular-fibrous tissue. The preparations were applied to a wound defect in the form of liniments. Silatranes were found to stimulate proliferation of the cells and to increase their biosynthetic activity, to favour accumulation of collagen and non-collagenic proteins, and reduction of the inflammatory phenomena.

[Use of silatranes in combination with Vishnevskii'n ointment in wound treatment].

Experiments on rats were performed to study the effect of I-/chlormethyl/silatrane and I-/ethoxy/silatrane as well as that of triethanolamine and /chlormethyl/triethoxysilane on the biochemical characteristics of granular-fibrous tissue. The drugs were applied to the wound in the form of liniments. Silatranes stimulated cell proliferation and raised biosynthetic activity of the cells.

[Effect of silicoorganic compounds on protein biosynthesis in granulation-fibrous tissue].

The authors studied the effect of propoxysilatran (POS) on the biosynthesis of the main connective tissue biopolymeres. The use of POS in the form of 0.5 and 2.